Also in Global Health news: Positive deviance method of health.

Also in Global Health news: ‘Positive deviance’ method of health; kid malnutrition in Madagascar; Somalia’s health system; fragile harvests in West Africa; improving health equity Boston World Examines ‘Positive Deviance’ METHOD OF Improve Health The Boston Globe examines ”positive deviance,’ a procedure for behavioral and social modification. Instead of imposing solutions from without, the method identifies outliers in a community who, despite having no particular advantages, are doing well exceptionally. By respecting regional ingenuity, proponents say, the approach galvanizes community members and is more effective and sustainable than imported blueprints often .’ This article includes examples in which ‘positive deviance’ was used to address malnutrition and curb baby death rates .

This protecting effect was dose durable and responsive, with an individual dose administration producing a protective impact that lasted for at least two weeks. Further, in a treatment model, a single dose of ALAS-1 siRNA quickly reduced the high levels of plasma ALA and PBG that were elevated throughout a phenobarbital-induced acute assault. Further, preliminary comparative studies also show that ALAS-1 siRNA administration was more effective than heme administration in the treatment of an acute assault. Finally, the company presented results from its ongoing GalNAc-siRNA conjugate efforts enabling subcutaneous dose administration.

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